honeybee
Researchers
We are interested in understanding the cause of cannabis withdrawal syndrome and how it affects the brain. We are looking for participants who are 19-65 years of age who regularly use cannabis are willing to abstain from using cannabis for approximately 1 week.
More information may be found at: http://camhstudies.ca/cgi-bin/findCAMHstudy_study.php?d=244
The objective of the proposed study is to use PET imaging using a tracer ([C-11] CURB) to visualize a protein in the brain (FAAH). We want to investigate whether FAAH levels in the brain contribute to withdrawal symptoms.This study will provide the first long term data on how cannabis related molecule metabolize in the brain during metabolism cannabis withdrawal.
You must be 19-65 years
You must have recently experienced problems with excessive cannabis use - you must use cannabis everyday
You must not have an unstable medical condition
You must not have current psychiatric disorders
You must not have past or current neurological illness or head trauma
You must not have a history of suicide attempts or suicidality
You must not have metal implants in your body
You must not be pregnant or breastfeeding
You cannot have claustrophobia
Your exposure to radiation in the past 12 months cannot exceed the permissible limit for subjects participating in research
029-2017
Health and Wellness
Clinical Trial
Weekdays
30 minute(s) - 4 hour(s) per session
4 session(s)
The study has three parts: - An in-person interview - Two - three MRI sessions - Two - three positron emission tomography (PET) scans - Abstinence monitoring sessions in between PET scans (~1hr per session)
$800
All meals on scan days covered
All transportation covered e.g. round trip public transportation and in special occasions taxis and Ubers
250 College St Toronto, Ontario, Canada, M5T 1R8