Mild asthma induced by cat or house dust mite allergy study

Cliantha Research, Clinical Research Organization (CRO)


The primary purpose of this study is to assess if the Test product (ADX-629), is safe and effective to treat mild asthma brought on by allergens in comparison to a Placebo.

Eligibility Criteria


Male, Female

18 to 65 years old

2-year medical history of mild asthma

Allergy to house dust mites (HDM) or cats

No recent hospitalization with asthma in the last 6 months

Has not received allergen immunotherapy treatment with cat or HDM within the previous 5 years

Ability to tolerate temporary withdrawal of current asthma medication

Non-smokers within the past 1 year having not used tobacco products (i.e. cigarettes, cigars, pipe tobacco) or electronic cigarettes or other inhaled nicotine delivery products

Other inclusion/exclusion criteria will be assessed

Study Tasks


Informed Consent Document (ICF)
Medical history and demographics
Measurement of vital signs and physical examination
Asthma control questionnaire
Skin prick test (SPT) to show positivity to cat or HDM allergen
Spirometry to assess lung function
Other tasks will be outlined during the ICF process
COVID-19 screening/testing

Ethics


This study has been approved by Advarra Ethics Board

Keywords


Clinical trial
asthma
Cat allergy
House dust mite allergy
Allergies

Activity and Time


Investigational Medicine

Clinical Trial

Weekdays, Weekends

75 days total, 13 sessions

Initial phone screening will be conducted by the recruitment team and then followed by a clinic phone assessment to determine eligibility prior to medical screening. The study consists of 13 in-clinic visits, two at home treatment periods and two 2-week washout periods at designated time points. COVID-19 testing will be conducted prior to designated visits.

Compensation


Up to $4060 

Study Address


4520 Dixie Rd Mississauga, Ontario, Canada, L4W 1N2

Posting date: Dec 16, 2020

Earn $4060