Mild asthma induced by cat or house dust mite allergy study
Cliantha Research, Clinical Research Organization (CRO)
The primary purpose of this study is to assess if the Test product (ADX-629), is safe and effective to treat mild asthma brought on by allergens in comparison to a Placebo.
Eligibility Criteria
Male, Female
18 to 65 years old
2-year medical history of mild asthma
Allergy to house dust mites (HDM) or cats
No recent hospitalization with asthma in the last 6 months
Has not received allergen immunotherapy treatment with cat or HDM within the previous 5 years
Ability to tolerate temporary withdrawal of current asthma medication
Non-smokers within the past 1 year having not used tobacco products (i.e. cigarettes, cigars, pipe tobacco) or electronic cigarettes or other inhaled nicotine delivery products
Other inclusion/exclusion criteria will be assessed
Study Tasks
Informed Consent Document (ICF)
Medical history and demographics
Measurement of vital signs and physical examination
Asthma control questionnaire
Skin prick test (SPT) to show positivity to cat or HDM allergen
Spirometry to assess lung function
Other tasks will be outlined during the ICF process
COVID-19 screening/testing
Ethics
This study has been approved by Advarra Ethics Board
Keywords
Activity and Time
Investigational Medicine
Clinical Trial
Weekdays, Weekends
75 days total, 13 sessions
Initial phone screening will be conducted by the recruitment team and then followed by a clinic phone assessment to determine eligibility prior to medical screening. The study consists of 13 in-clinic visits, two at home treatment periods and two 2-week washout periods at designated time points. COVID-19 testing will be conducted prior to designated visits.
Compensation
Up to $4060
Study Address
4520 Dixie Rd Mississauga, Ontario, Canada, L4W 1N2
Earn $4060